Astroglial Alterations in the Hippocampus of Rats Submitted to a Single Trans-Cranial Direct Current Stimulation Trial – Lol, I guess I haven’t posted anything about tDCS for awhile but it looks like there’s finally some scant support for my hypothesis about it’s effectiveness. Reading very slightly between the lines, this work implies that tDCS modifies …
Combining S100B and Cytokines as Neuro-Inflammatory Biomarkers for Diagnosing Generalized Anxiety Disorder: A Proof-of-Concept Study Based on Machine Learning – Hadn’t considered using interleukins specifically like this, hrm… Alteration of the neuronal and glial cell profiles in Neu1-deficient zebrafish – Hahah, “autistic” zebra fish. The role of astrocytes in behaviors related to emotion and motivation …
Dump of Astrocytes and Anxiety/Depression (aka DAAD is a funny acronym). Read More »
Can’t find anything on youtube for that title, was a song we sang at summer camp that went something like “Announcements… what a horrible way to die, what a horrible way to die, what a horrible way to spend the day, announcements”. Or something like that. Yes, I bind information directly sensory stimuli, what of …
Announcements, Announcements, Annoooouuncements. Read More »
The placenta epigenome–brain axis: placental epigenomic and transcriptomic responses that preprogram cognitive impairment – Genes are important, but it’s expression that matters. I dunno about the “placenta-brain” axis thing though. Human white matter myelinates faster in utero than ex utero – Heh, white matter is white because of myelination (and fibrous cell types). A new …
Notes to fill in later: Heterogeneity of expression Overlap between ADHD and trauma response Big astrocytes, little connections Conforming to existing data Why does “ADHD” look so much like dorsal flavors of “autism”? Edit: Still working on this. Associations Between Adverse Childhood Experiences and ADHD Diagnosis and Severity – OR isn’t great here, but this …
Association between enlarged perivascular spaces and cerebrospinal fluid aquaporin-4 and tau levels: report from a memory clinic – AQP “over-expresses” in response to misfolds/gunk in an attempt to clear it. Makes sense. Control of blood capillary networks and holes in blood-brain barrier models by regulating elastic modulus of scaffolds – It’s just physics baby. Hypothalamic …
The idea has been percolating in my brain for a few weeks that our understanding of “how DNA works”, particularly in regard to expressed behavior, might rest on similar philosophical pitfalls that led to the over application of neuron function in the study of nervous systems. We’ve assumed that DNA construction guides expression because we …
A primary point of divergence for the model is the assertion that electro-chemical processes are actually an artifact of mechanical forces. When we measure “electrical” function in cells, we are actually inferring the mechanical processes which generate the gradients. Mechanosensitive Piezo1 Channel in Physiology and Pathophysiology of the Central Nervous System – All cells are …
Been thinking quite a bit lately about the mechanics of how DNA and RNA interact, and more specifically how RNA is constantly shaping DNA in response to external environment. I’ve been caught up on the idea that every cell in every organism is the result of a sustained chemical reaction stretching back billions of years …
