Hippocampus is a “high level” stream processor, it integrates into “maps” (and decomposes from “maps” to more discrete levels) our sensory stream. These maps are referenced to other functional nuclei throughout the nervous system. The “Dorsal” portion of the hippocampus is responsible for “external” stimuli processing, the “Ventral” portion of the hippocampus is responsible for …
NIH Preprint Pilot – Looks like any research with NIH funding is eligible? Maybe this will lead to better incorporation of in process studies, and more importantly include more work with “failed”/”inconclusive” hypotheses? I like the idea of removing yet another economic barrier to information on the research side, but it also gives me pause …
https://onlinelibrary.wiley.com/doi/full/10.1002/adbi.202200269 Damn this is cool work. So they managed to note that astrocytes can processes multiple stimuli concurrently, and demonstrates how they remodel themselves to reflect that processed information. It further demonstrates how this has a downstream effect on other cells, like neurons. Information is stored local to the astrocyte, then encoded into local group …
My family and I have been sick for the past week or so, and during that time this topic popped into my head as I watched the difference between onset and recovery of symptoms between each family member. Every cell in our bodies have an innate immune response to various insults, for example interferon pressure …
Second thoughts about epigenetic information and aging. Read More »
Has there been any research regarding genetic variation of our microbiome longitudinally? Is there maybe a correlation between these outcomes and regional variation in microbiomes? Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression – God I fucking hate hypothesis based science, can support absolutely any ridiculous argument. …
Cognitive processes seem to have two discrete stages, “input/output” and “integration”. The I/O stage is well preserved and exists across in almost all animals (sponges gotta sponge), and is the simple process of linking stimuli with “memory/behavior”. In mammals this I/O occurs in the first three cortical layers (birbs as well, but their palliums have …
Thinking about how most of our early education is essentially writing in a standardized processing order, and how expensive deviations from that processing order get as the processing order gets more complex. For example, it’s “easier” to learn basic concepts, particularly as a child, when the pre-existing dependencies are low, but as we add more …
This is my first really theoretical post and may need some refining and adjusting when more evidence comes in, so be warned the specifics of this are lower confidence than normal. This post covers a wide range of “disorders of consciousness” including “autism/schizophrenia” and most “personality disorders”. Necessary assumptions: The adaptive portion of nervous systems …
When I first started on this path, I think one of my primary questions (whether I was aware of it or not) was not so much “How do brains work?” but “How does behavior work?”. I think this is largely shaped by the view of nervous systems as facilitators of behavior, rather than interesting in …
