One of the big revelations from the last few years worth of focus on glia is shining a light on how we learn. Astrocytes create non-overlapping local domains, and each local domain is essentially stored information is the core of the learning process. Astrocytic local domains have a maximum amount of discrete information available (capped …
There have been many attempts to repair nervous system damage, the most recent trend is to use electronic devices to bridge a signalling gap around an insult. These have all predictably failed despite early promise, in my opinion because they still carry a neuron-centric/electric brain view of nervous system function which has fairly significant flaws. …
Big Breakthroughs Soon in Nervous System Regeneration/Reconfiguration? Read More »
I’m currently gathering information in an attempt to build a model which gives some insight on the possibility of some unsettling trends in dementia and dementia like conditions in the near future and I’m left with some pretty unsettling questions. Many people have read the book “Freakonomics” which proposed that abortion legality showed strong correlations …
One of the primary conceits in my current model is the concept of “Dorsal/Ventral” streams. My original inception to this idea came from hippocampal work which specifically noted differential activity of dorsal vs. ventral regions of the hippocampus, and after exploring other brain structures discovered that most of them also have histologically distinct divisions. My …
Exaly – One of my favorite sites, particularly the trends graphs. Makes it easy to see when a particular topic’s research is getting disconnected from citations, an indication that replication/reproduction on the topic is failing. Also super helpful to observe how a topic has grown over time, and current “enthusiasm” for a topic. Pubpeer – …
One of the oddest artifacts of astocytes in particular is that despite their morphological complexity, they do not overlap in “normal” development. They have varying density by region and by individual, but the cells themselves maintain discrete local environments. This coupled with every developed astrocyte having unique properties serves to answer one of the big …
Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement tfUS dump
Is it possible that our metabolic processes are multiple tiered, with oxygen dependent processes being only the most recent/top level process? What mechanism in the selective process would allow us to completely abandon the nitrogen breathing/dependent process? Do brains work by balancing different metabolic processes against each other? Perhaps not nitrogen fixing, but a balanced …
From nitrogen to oxygen and everything in between. Read More »
