One of my favorite youtube channels Thought Emporium has started series of shorts which explore the pathfinding/maze solving abilities of single celled organisms. A very cool look at biological science possibilities outside of the lab, and an illustration of how anyone can replicate existing science to verify their expectations/predictions. Short 1 Short 2
Open to volunteers and/or ideas here. I spun up this forum mostly as a place where I could scratchpad ideas based on a ground up follow the data kind of approach mostly because I was kind of shocked at how ineffectual current neuro/psych understandings are in predicting anything useful. The primary impetus of the site …
Ermagerd. The tl;dr is that astrocyte networks transmit interdependently of neurons and represent a discrete signalling network. Astrocytes also have the ability to modify activity of neurons in completely different regions (can control the entry and exit of a signal). Edit: Astrocyte domains and the three-dimensional and seamless expression of consciousness and explicit memories – …
DNA Methylation and Establishing Memory – I don’t recall reading this paper, but it’s so sympatico with the RNA based memory/mechanics of stimulation posts I’ve made. It’s still stuck on the neuronal/cortical models, but it’s a good introduction to the concept of how RNA create engrams and how stimulation (like tDCS) may modify behavior even …
‘MTL knew’: Misconduct allegations independently corroborated in private correspondence to special committee They finally flagged the paper – APP binds DR6 to trigger axon pruning and neuron death via distinct caspases Stanford University president announces resignation over concerns about his research Over 800 citations, with the most recent coming within the last few months.
Astroglial Alterations in the Hippocampus of Rats Submitted to a Single Trans-Cranial Direct Current Stimulation Trial – Lol, I guess I haven’t posted anything about tDCS for awhile but it looks like there’s finally some scant support for my hypothesis about it’s effectiveness. Reading very slightly between the lines, this work implies that tDCS modifies …
A systematic literature review on the role of glial cells in the pathomechanisms of migraine IL (Interleukin)-15 Bridges Astrocyte-Microglia Crosstalk and Exacerbates Brain Injury Following Intracerebral Hemorrhage Glia Signaling and Brain Microenvironment in Migraine Astrocytic Glutamate Transporters and Migraine Energy Metabolic Disorder of Astrocytes May Be an Inducer of Migraine Attack
One of the primary differentiators between being identified with “autism” and not is the level of cognitive performance across different categories. An individual with “normal” to “above average” cognitive measurements across all measured categories is likely to escape “detection”, while an individual with low or extremely uneven performance is dramatically more likely to be considered …
Unnecessarily Controversial and Definitely Undersupported: “Autism” and serial murder Read More »
Occasionally I get asked why I’m so dour about the utility of implantable technology, especially when it may solve very hard problems. Usually my response is something along the lines of they are awful now, are inaccessible to most, and if the underlying conceits are right we should have non-invasive options able to do the …
