We do not experience the world, only our reaction to it. Examples: Nervous systems do not store “ball” or “sound”, they encode the physiological responses to those stimuli which are constructed into objects via downstream processing. This bridges the “stimuli == memory == behavior” conceit. How do sensory illusions work? Oh wow, the thing where …
(shit, should have typed “nervous systems”) (also have to stop reverse Betteridging stuff, it’s a dumb habit) Imaging the electrical activity of organelles in living cells Lysosomes as dynamic regulators of cell and organismal homeostasis A lysosome-centered view of nutrient homeostasis – Some interesting arguments despite the age. The direct piezoelectric effect in the globular …
(WIP) Life does not happen without stimuli. It becomes alive only through the constant metabolism/catalysis with “the world” external to the cell (or whatever we define as the minimum quanta of life for the virus/RNA/RNP fans). The action of this metabolic/catalytic process, which serves as the foundation of our definition of biological life, is the …
https://www.jneurosci.org/content/early/2023/03/06/JNEUROSCI.1982-22.2023.long I’m metaphorically screaming right now. This is the piece of confirmatory evidence I’ve been waiting for since I saw this. Something I really love about this particular work is it demonstrates a homeostasis point, “too much” is as important a mechanic as “too little”. Only doing a knockout isn’t enough to really understand the …
Sorry another stub for now. Sparked by this study Association between mitochondria-related genes and cognitive performance in the PsyCourse Study (which is a bad study with the right idea), we should be able to measure all components of cognitive ability via metabolic interactions, including things like g. As information processing in general is the product …
Aquaporin water channels affect the response of conventional anticancer therapies of 3D grown breast cancer cells Aquaporins in Nervous System Cerebral Microcirculation, Perivascular Unit, and Glymphatic System: Role of Aquaporin-4 as the Gatekeeper for Water Homeostasis Human Aquaporins: Functional Diversity and Potential Roles in Infectious and Non-infectious Diseases Cellular Distribution of Brain Aquaporins and Their …
https://safjan.com/pros-and-cons-of-reliance-on-ai-generating-models/#pros-and-cons-of-reliance-on-ai-generating-models I think the “AI” tie in is dumb, but the underlying question, whether or not our cognitive skills are trainable and evolving vs. the fixed physiologically encoded things that cogsci assumes is a really interesting question. Are we as a species self selecting individuals with an entirely new class of information processing capabilities that …
New Cognitive Skills in the Age of AI Tailored Information Presentation Read More »
I realize that over the last few weeks I’ve left quite a few open posts that I should probably complete. I’ve been having sleep issues the last month (well my kids have, therefore I do as well) so my mental energy has been kind of in the toilet (glymphatic system hasn’t had the opportunity to …
Actually, other way around. Base units would be limited to SGZ/SVZ post puberty/hypothalamic transfer in ventral phenotypes. What a fascinating dynamic, and provides a remarkably coherent mechanical explanation for the shift in learning patterns over a lifespan. Floor is a huge blindspot right now, which is kind of weird because that’s were a lot of …
Are new base memory units increasingly limited to the 4th ventricle post puberty? Read More »
