Was thinking a bit about how we could get over some of our information limitations in regard to breadth of data collected, and am wondering if we can replace electrophysiological devices with optical ones? We might even be able to do it fairly cheaply considering COTS sensors can create pixel widths >.5 micron already. There …
Treat this post the same as you would one of the dump posts for now, I’m just spitballing (what a weird idiom) integration of ideas from the past year to see if we can come up with new approaches to current questions. This is going to be edited in place so I’ll start with outlines …
It’s becoming pretty clear that when we start showing elevated levels of GFAP or other astrocytic markers in the adult blood stream, it’s an indication that something is going wrong. Work has been done which correlates GFAP level as a biomarker for dementias (from Alzheimer’s to vascular and everything in between), most cancers, renal and …
Should serum GFAP be part of the standard panel for medical physicals? Read More »
Musk’s bid to start Neuralink human trials denied by FDA in 2022, report says The denials themselves are legally confidential to protect investor interests, but I have very little doubt this is true. In their last presentation, it was a total engineering clusterfuck with the head engineer’s biggest insight being that “the brain is squishy”. …
Unnecessary Follow Up: Neuralink human trial authorization denied. Read More »
So this is largely a social commentary, which admittedly is outside of my lane, but it’s a pervasive enough conceit that it’s starting to influence the type and quality of research being produced regarding nervous system function. I won’t beat around the bush, I hate the term “neurodiversity”. It’s a meaningless and harmful conceit which …
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies – Looks like the mechanics underlying glial encoding of information to neurons is pretty well preserved. Editorial: Cell biology of brain development and evolution – I’ve been thinking about the developmental effect on infants of sleep in hyperoxygenated/hyperbaric …
All we are is just another dump on the wall (Just a link dump) Read More »
The title is cribbed from one of the most overlooked papers/commentary (IMO) of all time in neuroscience. The article is based on the work of a pediatrician who was investigating the longitudinal effects of hydrocephalus, a condition in which the brain fills up with CSF and this compresses or retards the growth of brain structures. …
If you have a highly weighted ventral fear context (fear of the external harming the self), you probably should avoid this thread. This is not in jest. I wish Reddit had a way to produce a blank page easily. This thread is a work in progress, a continuation of the symbiont/parasite conceit I’ve been on …
The world’s oldest person made it to 122—3 reasons she lived so long, from a longevity expert who knew her 1 – Be Rich.2 – Don’t smoke (and by inference, similarly health impacting things).3 – Avoid work and stress all costs. Bonus – Have a decent social life. Doesn’t matter how much metformin you mainline …
Most accurate article on the secret to longevity to date Read More »
