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Question: Has neuroscience (outside of drug research for specific applications and arguably some physical insult treatments) had any significant impact on… anything?

Maybe a better way to phrase this is if neuroscience is actually advancing anything in terms of real world effect? I keep looking at dementia work and it’s just depressing, all this effort into understanding and it seems like hardly anything has reached down to the level of improving/changing day to day lives. The “mental …

Question: Has neuroscience (outside of drug research for specific applications and arguably some physical insult treatments) had any significant impact on… anything? Read More »

Yet another hippocampus dump

Hippocampus is a “high level” stream processor, it integrates into “maps” (and decomposes from “maps” to more discrete levels) our sensory stream. These maps are referenced to other functional nuclei throughout the nervous system. The “Dorsal” portion of the hippocampus is responsible for “external” stimuli processing, the “Ventral” portion of the hippocampus is responsible for …

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Decoding Natural Astrocyte Rhythms: Dynamic Actin Waves Result from Environmental Sensing by Primary Rodent Astrocytes

https://onlinelibrary.wiley.com/doi/full/10.1002/adbi.202200269 Damn this is cool work. So they managed to note that astrocytes can processes multiple stimuli concurrently, and demonstrates how they remodel themselves to reflect that processed information. It further demonstrates how this has a downstream effect on other cells, like neurons. Information is stored local to the astrocyte, then encoded into local group …

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Tin Foil Hat Time: Are changes to our microbiomes driving significant behavioral changes, or put another way, driving the incidence rates of obesity and neuro-developmental/neuro-degenerative conditions?

Has there been any research regarding genetic variation of our microbiome longitudinally? Is there maybe a correlation between these outcomes and regional variation in microbiomes? Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression – God I fucking hate hypothesis based science, can support absolutely any ridiculous argument. …

Tin Foil Hat Time: Are changes to our microbiomes driving significant behavioral changes, or put another way, driving the incidence rates of obesity and neuro-developmental/neuro-degenerative conditions? Read More »

Memory and Behavior

Cognitive processes seem to have two discrete stages, “input/output” and “integration”. The I/O stage is well preserved and exists across in almost all animals (sponges gotta sponge), and is the simple process of linking stimuli with “memory/behavior”. In mammals this I/O occurs in the first three cortical layers (birbs as well, but their palliums have …

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What is the metabolic cost difference between writing new information and conforming information?

Thinking about how most of our early education is essentially writing in a standardized processing order, and how expensive deviations from that processing order get as the processing order gets more complex. For example, it’s “easier” to learn basic concepts, particularly as a child, when the pre-existing dependencies are low, but as we add more …

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Order of Consciousness – High Level

This is my first really theoretical post and may need some refining and adjusting when more evidence comes in, so be warned the specifics of this are lower confidence than normal. This post covers a wide range of “disorders of consciousness” including “autism/schizophrenia” and most “personality disorders”. Necessary assumptions: The adaptive portion of nervous systems …

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