Personal Stimulation Experiments and Data Ref Dump: Whole Body Vibration Improves Spatial Memory, Anxiety-Like Behavior, and Motor Performance in Aged Male and Female Rats – Aids glymphatic clearance, particularly as low frequency waves subside with age? How much does specific frequency matter for efficacy? Test whole sweep down to 1hz cohort style? Does tolerability depend […]
Main points – These “conditions” represent a significantly different memory mechanic representing the world than “normal”. “HfA” (I need to come up with a better word than “autism”, I’m so done with it) types have an “objectless” memory paradigm and imagine things as collections of properties rather than objects to bind things to. Asperger’s represents
Transcranial focused ultrasound, pulsed at 40 Hz, activates microglia acutely and reduces Aβ load chronically, as demonstrated in vivo Clinical Intervention Using Focused Ultrasound (FUS) Stimulation of the Brain in Diverse Neurological Disorders Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans Transcranial Focused Ultrasound (tFUS) and Transcranial Unfocused Ultrasound (tUS) Neuromodulation:
I’m having a rough time finding any condition which can be directly tied to neuron dysfunction rather than glial dysfunction. Dementias at this point are pretty clearly glial, there are no viruses I’m aware of that preferentially select neurons, demyelinating conditions are about as obviously astrocytic in origin as it gets. If we step back
Are there *any* neurological conditions which aren’t glial? Read More »
Paper wasps form abstract concept of ‘same and different’ – Where there be glia, there be “self awareness”, “consciousness”, and “goal directed behavior” Comparative analysis of astrocytes in the prefrontal cortex of primates: Insights into the evolution of human brain energetics Multiple Receptors Involved in Invasion and Neuropathogenicity of Canine Distemper Virus: A Review Spatial
Delta-Opioid Receptors Mediate Unique Plasticity onto Parvalbumin-Expressing Interneurons in Area CA2 of the Hippocampus – CA2 modifies the “trisynaptic pathway” in real time, locks information flow direction. Lack of locking results in tripping balls. Crucial role for CA2 inputs in the sequential organization of CA1 time cells supporting memory – Perception of time is managed
Is this the core mechanic of “intuition”? Maybe rhinal cortexes? Interesting observation – synesthetic posts and communication seem a lot “simpler” (is that fair to say?), while aphantastic posts are verbose. Is this a hippocampal stapling/integration mechanic or an upstream association mechanic? Reading these descriptions is screaming context binding to me. Whoa, self realization time
Following this – couldn’t most immune-nervous system interactions see a benefit from this?
