Due to the mechanical nature of metabolic processes in cells, specific processes should generate discrete types of “sound”/vibrations. We should be able to use “sound” based tools in almost exactly the same way we use electrophysiological tools, except they should have far greater process sensitivity and be able to record against the entire range of …
Non-invasive research tool for system level research: Microphones Read More »
https://cdnsciencepub.com/doi/10.1139/bcb-2023-0008 Wen human study?
S100b:S100B Expression Plays a Crucial Role in Cytotoxicity, Reactive Oxygen Species Generation and Nitric Oxide Synthase Activation Induced by Amyloid β-Protein in an Astrocytoma Cell Line GFAP:Plasma and cerebrospinal fluid glial fibrillary acidic protein levels in adults with Down syndrome: a longitudinal cohort study
Same progenitors – Transdifferentiable – Interdependencies – tl;dr neurons, glia, etc are the same class of cells from the same precursor cells, and can be checkpointed into each other (mostly). I’m going to put time into writing a formal screed/book based around this conceit. I’ve been reluctant to do so in the past because this …
All information system cells (“nervous system”) belong to the same class of cells. Read More »
Crap, should have said “ability” not performance. Wow, this is tough to research, as anti-cholesterol medications are pretty heavily prescribed. My experience is that pharma companies tend to flood the research pool with ambiguous work to protect/promote their cash cows. Yeah, I’m interested in the relationship between LDL and HDL with regard to cognitive ability, …
Are cholesterol levels relative to diet a direct biomarker of cognitive performance? Read More »
I really love this conceit! Rather than the “nervous system”, which is based on the assumed functions of neurons, calling it the “information system” is not only a lot more descriptive, but accurate as well. It’s kind of fun attaching function to various structures as well, like calling the hippocampus the “lungs” of the information …
Rather than an out of control metabolic cascade in the case of epileptic activity, this would be represented by a suppression of metabolic activity in a particular region like an “anti-seizure”. Most analgesics are anti-inflammatories which serve to open up the nerve pipes and reduce subjective pain. If we think about common occurrences of headache …
Calcium signaling in astrocytes and gliotransmitter release – The sooner electric brain goes away, the sooner we move forward. If only they had measurable zaps, we’d put some respect on their name. Are cytoskeleton changes observed in astrocytes functionally linked to aging? – It’s an interesting question, is this the functional equivalent to the Sinclair-esque …
https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd225047 Maybe not TCE by itself, but the whole class of pervasive industrial chemicals are definitely setting us up for a bomb (which we are probably in the midst of experiencing right now, just largely undiagnosed).
