Future medicine: from molecular pathways to the collective intelligence of the body – Intelligence from the spaces in between. (should note I’m conflicted about one of the authors on this one, great ideas but everything is through an “AI” lens which is interesting but not interesting)
The Multiple Realizability of Sentience in Living Systems and Beyond – Front runner for commentary style paper of the year. Sans the focus on “Artificial Intelligence”, the discussion in this paper is exactly the theme of this site.
Cellular signaling pathways as plastic, proto-cognitive systems: Implications for biomedicine – Stating the dangerously obvious with regard to most tractonomic or “network” based neuroscience; THE PATHWAYS AREN’T STATIC. As we continue trying to dump more and more time and effort into creating yet another construct which only exists as an average and applies to no individual, let’s take a moment to at least acknowledge the huge gaping pit these hypotheses impart.
Glial tone of aggression – Some of these experiments man, I just don’t know. Fucking mouse fight club is just a lot to process. Interesting results nonetheless.
A heritable iron memory enables decision-making in Escherichia coli – Daaaaaaaaaaaaaaamn. Very nice.
mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory – Lots of interesting bits here. Wish they had extended from CA1 to the subiculum, which has a pretty good chance of also being active in the stack stapling.
Reduced neural progenitor cell count and cortical neurogenesis in guinea pigs congenitally infected with Toxoplasma gondii – So my understanding is toxo suppresses cerebral cortical development but enhances cerebellar cortical development (e.g. “Aspergers”). This result is consistent with those expectations, wish we’d get around to the idea that the cerebellar and cerebral cortexes are inverted equivalents.