Over the past year one of the tools I’ve been developing is examining any set of information through a lens asking what if the construct being examined was literally anything else? The idea behind this is to assist in forcing generalization of the information being provided. What would happen if we changed the nouns in …
Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model – Interesting enough topic to make new post. This is one of the more sensical explanations for the mechanics of ketamine vs. “hard” depression, it aids in flushing the intercellular milieu, allowing new behavioral pathways to …
Breathing cluster in complex neuron–astrocyte networks – It’s kind of funny how much work starts off with something equivalent to “We thought astrocytes merely supported neurons, boy were we wrong – but we don’t have the nuts yet to say neurons are support cells yet.” Really fascinating part about this is that it suggests a …
Looks like I posted too many external links to Reddit for a new account and it thinks I’m a bot. Beep bop borp I guess. Welp, luckily the website is here for exactly this contingency. If anyone would be so kind as to post the links for new posts to the sub, that would be …
Hey there, and welcome. The amazingness that you see before you is a work in progress. At this point we are copying and cleaning up the posts on the [subreddit where this concept started](https://www.reddit.com/r/remodeledbrain), so it’s going to be a bit of a house in a tornado for a bit. So what is all of …
Jist of this is that at that all biological systems are based on repeatable, predictive chemical reactions. Biological systems have a complex set of interacting reactions, however we should be able to scale the predictiveness and repeatability of that chemistry even into human cognitive processes. This foundation also provides some interesting pathways for simplification of …
Direct current stimulation of endothelial monolayers induces a transient and reversible increase in transport due to the electroosmotic effect – This suggests tDCS (when effective) induces the changes in RNA expression by modifying the cellular osmotic pumps, rather than more directly modifying the transcription/translation process. This feels more correct than the model’s assumption of directly …
